The right probiotic
There is a multitude of different probiotic products on the market, all containing different strains of live bacteria, in different combinations and at different amounts – and this can make it difficult to decide which product to use in any given situation.
When deciding which to use, we would recommend using the probiotic that has a double-blind placebo-controlled trial published to support the specific condition that you are dealing with.
Whether it is irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), allergy, infection, gut-brain related disorders or simply alongside antibiotic use, it is efficacious to use strains that have been shown to provide a benefit for that particular condition.
In addition, a probiotic should include isolates that have been identified using the following criteria:
A species indigenous to the target host (human)
Capable of ‘colonisation’ of the digestive tract
Resistant to stomach acid and bile salts, capable of attachment to epithelial cells and capable of immunomodulation in-vitro.
Data to support use
Clinical data is particularly important.
Commercial release of the product should be covered by a thorough quality assurance program.
Lab4 and Lab4b
The Lab4 consortium of live bacteria used in the ProVen Probiotics products comprises four specially selected strains of lactobacillus and bifido bacteria found in the developed human GI tract. A separate group of four lactobacillus and bifidus strains was selected for babies (Lab4b) to reflect the bacteria present in the developing gut.
Lactic acid bacteria (Lactobacillus) and Bifidobacteria are considered to be benign microorganisms that are not associated with pathogenicity. In addition, the Lab4 bacteria have been rigorously tested to show both their passage through the GI tract and colonisation of the gut.
Prior to selection, the bacteria in the Lab4 consortia were subjected to a rigorous two-phase testing process to enable the most appropriate strains to be selected.
This two-stage process included preliminary and secondary screening for strain suitability, durability, ‘competitivity’, antimicrobial properties, antibiotic susceptibilities and growth and storage capabilities.
Multi-condition clinical data
But the ‘acid’ test is the efficacy of a particular probiotic in practice – does it stand up to its in-vitro characteristics in vivo?
The Lab4 consortia is supported by data showing benefits and symptom reduction in all of the following conditions:
This evidence supports the view that an effective probiotic will talk to different parts of our physiology and have effects in multiple systems at the same time. Currently, the Lab4 consortia of bacteria used in ProVen Probiotics is the leading probiotic group with ongoing, multi-condition clinical research to support this view.
Want to know more?
Pro-Ven Probiotics aim to provide the best support for both you and your health. If you wish to know more about gut health, and staying healthy please do not hesitate to call us on 01639 825107 or alternatively, learn more via our blogs or in-depth proven research.
ProVen Probiotics, Unit 2 Christchurch Road, Baglan Industrial Park, Port Talbot, SA12 7DJ. Tel: 01639 825107