The PROMAGEN Study: Quality of life

A randomised controlled study shows supplementation of overweight and obese adults with lactobacilli and bifidobacteria reduces bodyweight and improves well-being

SUMMARY

An exploratory, block-randomised, parallel, double-blind, single-centre, placebo-controlled superiority study with 220 overweight and obese adults with BMI 25-34.9. The probiotic group (110) took 50 billion Lab4P probiotics every day for six months and the placebo group (110) took an identical looking placebo.

Significant improvements in Quality of Life scores of general wellness, health, energy and mood were observed in the overweight and obese adults supplemented with Lab4P probiotics.

Aim

This randomised, double-blind, placebo controlled study aimed to assess the effect of 6-months supplementation with the Lab4P probiotic on body weight, plasma cholesterol and well-being in healthy overweight and obese individuals. The outcomes of the Quality of Life assessment are presented here.

Method

Results

  • Significant improvements in scores of State of Health (5.8%, *P< 0.05), State of Energy (5.5%, *P< 0.05) and State of Mood (5.1%,*P< 0.05) were observed at 3 months (Figure 1).
  • The Quality of Life assessment questionnaire covered these five areas; general wellness, state of health, state of energy, state of mood and sleep quality.
  •  6.3% significant improvement in General Wellness scores at 3 months (**P< 0.01) and 5.6% at 6 months (*P< 0.05) in the group supplemented with Lab4P probiotics (Group 2) compared to the placebo (Group 1).
  • Conclusion

    Supplementation of overweight and obese adults with the Lab4P probiotic resulted in a significant improvement of reported Quality of Life scores.

    Study links

    2020

    The PROMAGEN Study: Weight loss and Cholesterol

    A randomised controlled study shows supplementation of overweight and obese adults with lactobacilli and bifidobacteria reduces bodyweight and improves well-being

    2020

    The PROMAGEN Study: Viral pandemic link?

    Probiotics reduce self-reported symptoms of upper respiratory tract infection in overweight and obese adults: should we be considering probiotics during viral pandemics?

    2020

    The PROMAGEN Study: URTI Symptoms

    A randomised controlled study shows supplementation of overweight and obese adults with lactobacilli and bifidobacteria reduces bodyweight and improves well-being

    2021

    The PROBE Study

    Daily supplementation with the Lab4P probiotic consortium induces significant weight loss in overweight adults

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